• Skip to main content
  • Skip to footer

Vitality Radio

Vitality Radio with Jared St. Clair

  • Home
  • About Jared
  • Shop Vitality Nutrition
  • Vitality Radio Podcast
#571: Cracking the Code on Histamine Intolerance and Mast Cell Activation Syndrome

#571: Cracking the Code on Histamine Intolerance and Mast Cell Activation Syndrome

September 25, 2025 By Jared St. Clair

On this episode of Vitality Radio, we tackle one of the most overlooked and misunderstood health concerns of our time: Histamine Intolerance and Mast Cell Activation Syndrome (MCAS). These conditions often appear with “mystery symptoms” like skin issues, digestive discomfort, headaches, fatigue, and strange food or chemical reactions—many of which have surged in the post-COVID era. Jared explains what histamine really is, why your body sometimes produces too much of it, and how mast cells can become overactive, creating a flood of inflammation. You’ll learn about the role of DAO (Diamine Oxidase), the enzyme that helps break down food-based histamine, and why supplementing it can be a game-changer for many. You’ll also hear about supportive tools and practical strategies to lower your histamine load, calm mast cells, and rebuild gut health. If you’ve been dismissed, told it’s “just anxiety,” or left without answers, this episode offers clarity, hope, and practical steps to explore. Relief is possible—and it starts with understanding the root cause.

Products Discussed

Additional Information:

Blog: Histamine Intolerance MCAS (Mast Cell Activation Syndrome) with High Histamine Food List

Listen on your favorite podcast app including Apple or Spotify!

You can follow us on Instagram @vitalitynutritionbountiful and @vitalityradio, or on Facebook  and Twitter. Check us out online at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcast.

Filed Under: Uncategorized

Reader Interactions

Footer CTA

Listen to Past Vitality Radio Episodes

Listen Now

  • Facebook
  • Instagram
  • Twitter
  • Shop
  • Patreon
Copyright © 2020

Copyright © 2018 · VitalityRadio